NEET Solved Paper 2018 Question 83

Question: Which of the following events does not occur in rough endoplasmic reticulum? [NEET - 2018]

Options:

A) Cleavage of signal peptide

B) Protein glycosylation

C) Protein folding

D) Phospholipid synthesis

Show Answer

Answer:

Correct Answer: D

Solution:

A) Cleavage of signal peptide: This occurs in the RER. The signal peptide is a short peptide sequence that directs the nascent protein to the RER, where it is cleaved off by signal peptidase.

B) Protein glycosylation: This also occurs in the RER. Glycosylation is the process of adding carbohydrate groups to proteins, which is an important modification for protein folding and stability.

C) Protein folding: This occurs in the RER as well. The RER provides an environment for newly synthesized proteins to fold into their correct three-dimensional structures with the help of chaperone proteins.

D) Phospholipid synthesis: This does not primarily occur in the RER. Phospholipid synthesis mainly takes place in the smooth endoplasmic reticulum (SER), which is involved in lipid metabolism and synthesis.