NEET Solved Paper 2018 Question 83
Question: Which of the following events does not occur in rough endoplasmic reticulum? [NEET - 2018]
Options:
A) Cleavage of signal peptide
B) Protein glycosylation
C) Protein folding
D) Phospholipid synthesis
Show Answer
Answer:
Correct Answer: D
Solution:
A) Cleavage of signal peptide: This occurs in the RER. The signal peptide is a short peptide sequence that directs the nascent protein to the RER, where it is cleaved off by signal peptidase.
B) Protein glycosylation: This also occurs in the RER. Glycosylation is the process of adding carbohydrate groups to proteins, which is an important modification for protein folding and stability.
C) Protein folding: This occurs in the RER as well. The RER provides an environment for newly synthesized proteins to fold into their correct three-dimensional structures with the help of chaperone proteins.
D) Phospholipid synthesis: This does not primarily occur in the RER. Phospholipid synthesis mainly takes place in the smooth endoplasmic reticulum (SER), which is involved in lipid metabolism and synthesis.